Hearst Magazine Media, Inc. All Rights Reserved. All vaccines could cause some degree of reaction, and the same is true for COVID-19 vaccines. muscle aches. Chills. People with the O blood type (whether O positive or O negative) had a lower incidence of COVID-19 positive tests. If you haven't heard of the term "bivalent" just yet, it refers to the fact that this updated vaccine contains genetic code targeted to the original strain of virus that spreads COVID-19, known as SARS-CoV-2 in addition to parts of the Omicron-based strains that are circulating currently. Information on this website is provided for informational purposes only and is a result of years of practice and experience by the author. What this means is that the white blood cells that are stimulated by the vaccine to make antibodies themselves have to secrete chemicals called cytokines, interferons and chemokines, which function to send messages from cell to cell to become activated.. Yet these risks are relative, meaning people with type O blood are not immune to COVID-19. Is this true? "There's no way for us to predict how somebody is going to respond, but we know that the spectrum of severity is the same as what we've seen with original vaccines," Dr. Martinello adds. Why Trust Us? "We do not expect [the public] to experience anything that would be out of the ordinary from our experience with the original vaccination.". Although many vaccines can lead to hemolysis and thrombosis in PNH, this effect is mitigated in most patients on complement inhibitors. A protein called the Rh factor can also be present (+) or absent (-) from the blood. Is It Dandruff or Dry Scalp? "At the end of the day, we're still not sure if blood type makes a difference," said Dr. Russo. Muscle aches. As with all vaccines, side effects may occur after getting the COVID-19 vaccine. "Some evidence shows the severity of the infection is associated with different blood cell types, but the mechanisms by which it happens are unclear," says Dr. Anderson. "There is no real benefit for the individual person," said Torben Barington, DMSc, a clinical professor of immunology at the University of Southern Denmark and co-author of the early Danish study. But because reinfection is possible and COVID-19 can cause severe medical complications, it's recommended that people who have already had COVID-19 get a COVID-19 vaccine. Pain can be managed with acetaminophen, like Tylenol, or ibuprofen, Litwack said. Youve viewed {{metering-count}} of {{metering-total}} articles this month. Side effects in adults >55 after Pfizer-BioNTech vaccine (second dose) Pain at injection site (66.1%) Fatigue (50.5%) Headache (39.0%) Muscle pain (28.7%) Chills (22.7%) Joint pain (18.9%) Fever (10.9%), diarrhea (8.3%) and vomiting (0.7%) were also reported. Patients were aged 25 to 63 years, had PNH granulocyte clones of 80%, and had not received transfusions in the past year. Zee Krstic is a health editor for Good Housekeeping, where he covers health and nutrition news, decodes diet and fitness trends and reviews the best products in the wellness aisle. Do COVID-19 vaccines and boosters raise your blood sugar? - Case Studies Chills. How Long Does It Take for the COVID-19 Booster To Be Effective? Recent research is suggesting that your blood type may affect your risk of getting COVID-19 and could influence the severity of the disease. The information in this story is accurate as of press time. This study reported descriptive epidemiology for many potential AESIs for safety follow-up of COVID-19 vaccines from a random Swedish population. But an even better way to get your blood type tested is to donate blood, which, by the way, is still a safe thing to do, even during a pandemic. Side effects may even feel like flu and might affect your ability to do daily. "I encourage people who have had COVID once, or even multiple times to still seek out vaccination, as it's going to really optimize the level of protection that you have against getting COVID yet again this fall and winter," he advises. Fatigue. Lexington, MA 02421. This news story has not been updated since the date shown. These usually last from a few hours to a few days after vaccination. He subsequently was initiated on ravulizumab, a terminal complement inhibitor. Individuals with Type A blood type also represented a higher percentage of patients who succumbed to the illness 41 percent versus 25 percent for Type O. Those symptoms are similar in all vaccines, but in the two-dose vaccines, they are more common after the second shot. Registration is free. These acute stressors are like a "treadmill test for the pancreas," and the pancreas fails. For current information about MIT Medicals services, please see relevant areas of the MIT Medical website. Correspondence: Robert A. Brodsky, Division of Hematology, School of Medicine, Johns Hopkins University, 720 Rutland Ave, Ross Research Bldg, Room 1025, Baltimore, MD 21205; e-mail: brodsro@jhmi.edu. This work was supported by National Institutes of Health, National Heart, Lung, and Blood Institute grants R01 HL 133113 (R.A.B.) Contribution: G.F.G. Side effects are actually your body's idea - not the vaccine's. When you get a sore arm, fever or fatigue after vaccination, those reactions are your body's way of jumping into action to protect you. The lymph nodes become tender and swell up within two to four days after the COVID-19 vaccination, and the swelling can last up to six to eight weeks. Now, a "Covid arm" is different from a skin reaction that . Here's a list of the side effects to the COVID-19 vaccine, plus information on how experts track side effects and what reports of serious side effects mean. Even Mild COVID-19 Infections Increase Risk of Type 2 Diabetes, Research Shows, Journal of the American Medical Association, CDC guidelines to prevent the spread of COVID-19. A Top Derm Explains, 35 of the Smartest Fast-Food Choices You Can Make, Easy Brain Exercises to Boost Your Memory, Why We Should All Be Eating More Buckwheat, COVID-19 Emergency Funding Is Coming to an End. But if you understand how vaccines work, you'll know that experiencing a side effect isn't a sign that something's gone wrong. COVID Increases Risk of Long-Term Brain Injury, Study Shows. That is not to say that there have never been safety issues with vaccines. Reported side effects of COVID-19 vaccines have mostly been mild to moderate and have lasted no longer thana few days. 25 Carleton Street Common Moderna COVID-19 Vaccine side effects may include: fever, chills; redness or a hardness and swelling where the shot was given; swelling or tenderness under your arm; nausea, vomiting; feeling tired; or. Some less common side effects include nausea and swollen lymph nodes (especially in the armpit). All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. The risk with vaccines is exceedingly low and individuals are at a significantly higher risk of developing a blood clot from COVID-19 infection than following COVID-19 vaccination. S.C. has served on advisory boards for Alexion and Sanofi-Genzyme, and her institution has received research funding on her behalf from Takeda. Common Side Effects of COVID Vaccines After getting vaccinated for COVID-19, you might experience some temporary symptoms similar to those you might notice when you get a flu shot, such as a sore, swollen arm where you got the shot. "Masks are important because they filter out some of the virus and decreases the viral load, which makes the infection less severe," says Dr. Anderson. However, experts say it is too soon to be sure the J&J jab is causing the blood-clotting problem, and even if it is, the risk is very low. Patients with type O and rhesus negative (Rh-) blood groups may have a lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severe coronavirus disease 2019 (COVID-19) illness, according to a study published in the Annals of Internal Medicine. D-dimer was elevated to 0.73 g/mL fibrinogen-equivalent units from 0.21 g/mL. Blood clots in the arteries leading to the brain can cause a stroke. According to the AstraZeneca product monograph, more than one in 10 people will experience some of these very common side-effects: Pain or itching at the injection site. Feeling tired. While the distribution of blood types is different in New York City than in Wuhan and Shenzhen, after controlling for other risk factors, they found that individuals with Type A blood were 34 percent more likely to test positive for the coronavirus, while having Type O or AB blood was associated with a lower probability of testing positive. Sleep expert Dr. Michael Breus strongly advises that getting a good nights sleep is essential before you go in for the vaccine in order to build a healthy antibody response.7. Quite a bit of research has been published on the topic of blood type and its role in determining COVID-19 risk. This "Covid arm" rash can be red, itchy, swollen, or painful. Early in the pandemic, two studies published in the Blood Advances journal in October 2020 showed a possible link between blood type and vulnerability to COVID-19. In populations at high-risk for exposure, such as healthcare workers, essential workers, and people exposed to a known case of the disease, the O blood type had an even greater protective effect, reducing the risk of acquiring the virus by 19 percent. In the case of the two mRNA COVID-19 vaccines, well over 90% of people immunized developed the protective adaptive immune response while fewer than 50% developed any side effects, and most were mild. Should you eat before? These include soreness where the jab was. The latest data on blood type is still preliminary. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. Dr. Gundry and her team continue to investigate how heart injuries caused by COVID-19 developand the impact of red blood cells on the infection. However, according to the data, a tiny. Patient 1 had a presumptive thrombotic manifestation. But it's interesting to note that the severity of side effects caused by bivalent vaccines were reported as less severe; Pfizer's clinical trial found that less than 1% of patients experienced severe pain or headaches, whereas a majority of participants (52%) reported only mild pain at the injection site. Post-vaccine symptoms are typically mild and resolve quickly without the need to use any medication. A bigail, a 29-year-old from New York City who asked to use a pseudonym to preserve her privacy, knew to expect some side effects after she got her second Pfizer-BioNTech COVID-19 vaccine in . This preliminary safety signal has prompted additional investigation into whether . He has written about food and dining for Time, among other publications. Read More Safety of COVID-19 Vaccines Some people have no side effects. Furthermore, among ongoing clinical trials of immunotherapy using convalescent plasma or of SARS-CoV-2 vaccines, the interaction between participant blood groups and therapeutic efficacy could be measured.. "It'll be intriguing to see what we learn from this new study.". The studys primary outcome was SARS-CoV-2 infection. Knowledge of your blood type is usually important if you're undergoing a blood transfusion or organ transplantbut in those situations, your medical team will test your blood type beforehand. This material may not be published, broadcast, rewritten or redistributed in any form without prior authorization. Blood clot symptoms and when they're likely to occur. As seen in patients 3 and 6, a proximal complement inhibitor, such as danicopan, may prevent breakthrough hemolysis precipitated by the vaccine; however, it is equally possible that the stronger immune response after the second vaccine dose was primarily responsible for the breakthrough hemolysis in patient 3. Free download: Get the Body Ecology blood type ebook. The reduction in risk appeared to be about 9 to 18 percent for people with an O blood type compared with other blood types, among which there was little difference in susceptibility. Your friend would have a worse case of COVID-19 because they were infected with more virus. Since the formulation of this particular round of bivalent booster vaccines was made in a very similar process to earlier options, experts aren't expecting any new subsets of potential side effects to present this fall. - Drug Monographs We call this the viral load. Read said: We are a little baffled about this, but it may be due to the fact that the Oxford University/AstraZeneca vaccine has an adenovirus vector, which stimulates the immune system strongly in the first dose and less strongly in the second.. Type A blood was associated with a 45 percent increased risk of having respiratory failure, while Type O was associated with a 35 percent reduction in risk. Other countries have taken different approaches: in France the AstraZeneca jab is now only to be given to those aged 55 and over, while in Germany it is offered to those aged 60 and over. Hear the whys of three Black colleagues from Nebraska Medicine. What scientists have learned is blood type seems to matter in at least two ways: Recent data suggests that people with blood type A have a significantly higher risk of acquiring COVID-19 than non-A blood types. Lockard Conley Research Fellowship in Benign Hematology (G.F.G.). This variant is associated with a 12-percent reduced odds ratio of testing positive for COVID-19.1. Those two factors make up the eight most common blood types: A+, A-, B+, B-, O+, O-, AB+, and AB-. Muscle pain. The relative protective effects of O, Rh-, and O- blood groups were greatest in patients younger than age 70. According to Public Health England, most side-effects from two Covid vaccines - Pfizer/BioNTech and Oxford/AstraZeneca - are mild and short-lived. I have read that people with certainbloodtypes are more susceptible to contracting COVID-19. However, the results have been inconsistent and so the connection between COVID-19 and different blood types still isn't clear. The first hint of a possible relationship came in March, from researchers in China, who compared nearly 2,200 hospitalized COVID-19 patients to a control group of approximately 27,000 healthy individuals. She was also part of a clinical trial with danicopan, an oral complement factor D inhibitor. A side effect or reaction isn't necessarily all bad, by the way; it may indicate that the body is building protection against the virus. Vaccine side effects show up within weeks if at all. If any of these side effects occur, they should go away in a few days. Indeed, coagulopathy (problems with bleeding disorders) is common in COVID-19, with dangerous blood clots being a hallmark of the disease. You could . While the UK has ordered 30m doses of the J&J jab, it has not yet been authorised for use by the MHRA. One study published in the Journal of the American Medical Association (JAMA) in April of 2021, reviewed nearly 108,000 COVID-19 cases. Investigators conducted a population-based, retrospective cohort study of 225,556 patients who had their ABO blood group assessed between January 2007 and December 2019, and subsequently tested for SARS-CoV-2 between January 15 and June 30, 2020. Omicron vs. Delta: How the 2 COVID-19 Variants Compare, ShinglesHerpes ZosterInfection May Be Linked to the COVID-19 Vaccine. Additionally on danicopan; however, 2 doses were missed immediately following vaccination. It has also been identified as an extremely rare side effect of certain COVID-19 vaccines. Steam Room vs. Sauna: Which Is Better for You? Your friend sits next to the person infected. But again, experts say it's too early to know for sure. Some people experience a little discomfort and can continue to go about their day. This is called a breakthrough infection. The risk of death was increased for type AB and decreased for types A and B. designed research, analyzed data, and wrote the manuscript; and all authors reviewed the manuscript and approved the final version. If you have or suspect that you have a medical problem, contact your healthcare provider promptly. Hemolysis in each sample was compared with total water-induced lysis of the erythrocytes. Chills,. None of these patients were previously transfused in the past year. Side. A Vancouver study revealed people with blood types A, B or AB had worse outcomes than others. The online version of this article contains a data supplement. So, keep wearing that mask, socially distancing, and washing your hands actions that are proven to reduce the risk of illness for people of every blood type. S1 did not increase hemolysis of PNH erythrocytes as compared with aNHS alone (Figure 1). Blood 2021; 137 (26): 36703673. In the days following COVID-19 vaccination, your immune system responds to the vaccine. Centers for Disease Control and Prevention, you didn't experience any side effects at all, better bolster your body's immune response, other better-for-you fluids to stay hydrated, Your Privacy Choices: Opt Out of Sale/Targeted Ads, Take over-the-counter medication like ibuprofen, acetaminophen, aspirin, and antihistamines as needed, Apply a cold compress or a wet washcloth over the injection site if experiencing redness or swelling, Exercise your arm after injection to mitigate discomfort. Some previously young, healthy people who have developed COVID-19 have suffered strokes, possibly due . Researchers found no link between blood type and COVID-19 risk, adding that more research was needed on the topic. Reactions occurred from the day of administration to 5 days later and lasted 1 to 6 days. Headache. There have been multiple studies on blood types and COVID-19 risk. Diet is also key, and as you are probably well aware of by now if youve been following me a healthy microbiome is a must. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. Laboratory tests 1 week later, as symptoms were resolving, showed >4 g/dL hemoglobin decrease from his baseline. The other half is the adaptive response which learns and then remembers how to fight an infection by designing B . The other common side-effects the muscle aches, flu-like illness and fatigue are probably due to generalised activation of the immune system caused by the vaccine. Following his second dose, he noted fevers, diarrhea, vomiting, severe fatigue, and dark urine. He also developed hemoglobinuria on postvaccination days 1 and 2, associated with 2.7 g/dL hemoglobin decrease. For original data, please e-mail the corresponding author. There was also a moderately increased risk of infection in people with Rh-positive blood type. That means getting vaccinated and boosted, social distancing, wearing a mask in public, and washing your hands regularly, among other things. Common side effects included: tenderness at the injection site for 73% of participants. Neither Donna Gates nor Body Ecology, Inc., nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. In populations at high-risk for exposure, such as healthcare workers, essential workers, and people exposed to a known case of the disease, the O blood type had an even greater protective effect. With clinics and pharmacies across the nation (including CVS and Walgreens) now offering vaccination appointments, you may be curious to know more about this updated vaccine and what kind of side effects may be affecting you after the shot. That's because of a particular type of antibody they make that attacks other red blood cells. Four of 6 patients reported fever. The blood group types did not affect the clinical outcomes. For some people, the second [] In addition, his total bilirubin rose to 7.1 mg/dL from baseline 2.4 mg/dL. Published online November 24, 2020. doi:10.7326/M20-4511, Latest News Your top articles for Saturday, Continuing Medical Education (CME/CE) Courses. The Food and Drug Administration sees a possible risk of Guillain-Barre syndrome with Pfizer 's RSV vaccine for older adults and has asked the company to conduct a safety study if the shot is . What Are Side Effects of the COVID-19 Vaccines? It's been called COVID. 16 Furthermore, 3 instances of His symptoms resolved after 5 days. The analysis turned up gene variants in two regions of the human genome that were associated with severe illness and greater risk of COVID-19-related death. After adjusting for confounding factors, such as age, sex, race, ethnicity, BMI, and high-risk co-morbidity or being immunocompromised, those with blood type O were, on average, 14-percent less likely to acquire a COVID-19 infection and 19-percent less likely to be hospitalized for the infection. In short, it might feel like you have the flu. Acute stressors such as pregnancy, steroids or inflammation from cytokine activation often seen in COVID-19 patients can bring out hyperglycemia in someone not known to have diabetes/prediabetes. Remember that 70 percent of your immune system is determined by the microbiome in your gut.8 At Body Ecology, we promote the use of certain (but not all) fermented foods to not only nourish you but to nourish your gut and immune system as well. These studies are fascinating from a scientific perspective, but at this point, they have no practical implications for the way we live our lives and the precautions we should be taking to protect others and ourselves. The aRR for SARS-CoV-2 infection in the O blood group was 0.88 (95% CI, 0.84-0.92) vs all other blood groups, and the ARD was -3.9 per 1,000 (95% CI, -5.4 to -2.5). You asked, we answered: Does vaccine herd immunity work? They observed that individuals with Type A blood appeared to be at significantly higher risk of contracting the virus constituting nearly 38 percent of the ill patients, compared with the 31 percent of healthy individuals with this blood type. We also present 2 patients with PNH who received the vaccine without significant adverse effects or hemolysis. Headache. Adverse reactions appear time-limited and can be managed with supportive care and transfusions as needed. One of the most unusual and serious side-effects of the COVID-19 vaccine jab, which has been reported from various corners is Blood clotting. Computed tomography with contrast showed peripancreatic fat stranding with normal lipase, concerning for possible small bowel microvascular thrombosis. Some data suggests this may be the case. doi: https://doi.org/10.1182/blood.2021011548. In addition, COVID-19 vaccination might offer better protection than getting sick with COVID-19.A recent study showed that unvaccinated people who already . fatigue for 50% of the participants. Enjoying our content? You might run a fever and experience body aches, headaches and tiredness for a day or two. But no vaccine is 100% effective, so some people who are fully vaccinated might still become infected with COVID-19 and get sick. No change is recommended in COVID-19 vaccination practice. All in all, more than 1 million people were involved. One study of over 3,000 people who got a COVID-19 vaccine did not find any increased side effects or other issues among people with different blood types. Similarly, type B individuals only have anti-A antibodies. "We do know that people of all types can get infected with COVID-19," says cardiologist Daniel Anderson, MD, PhD. "People with type O blood may be more susceptible to norovirus," said infectious disease expert Amesh A. Adalja, MD, senior scholar at the Johns Hopkins Center for Health Security. Your use of this website constitutes acceptance of Haymarket Medias Privacy Policy and Terms & Conditions. 2. Still, the study authors wrote, "the impact of blood type on clinical outcomes remains unclear. By signing up, you are consenting to receive electronic messages from Nebraska Medicine. Researchers think the clotting may be triggered by the high . So, it seems that not only does your blood type affect your risk of getting COVID-19, it may also affect your chances of needing serious medical intervention and of survival. This unusual clotting may cause different complications, including organ damage, heart attack and stroke. If so, how can I get that information? .css-lwn4i5{display:block;font-family:Neutra,Helvetica,Arial,Sans-serif;font-weight:bold;letter-spacing:-0.01rem;margin-bottom:0;margin-top:0;text-align:center;-webkit-text-decoration:none;text-decoration:none;}@media (any-hover: hover){.css-lwn4i5:hover{color:link-hover;}}@media(max-width: 48rem){.css-lwn4i5{font-size:1.375rem;line-height:1.1;}}@media(min-width: 40.625rem){.css-lwn4i5{font-size:1.375rem;line-height:1.1;}}@media(min-width: 48rem){.css-lwn4i5{font-size:1.375rem;line-height:1.1;}}@media(min-width: 64rem){.css-lwn4i5{font-size:1.375rem;line-height:1.1;}}Steam Room vs. Sauna: Which Is Better for You? Of course, your blood type is not a risk factor over which you have any control. performed research, collected and analyzed data, and wrote the first draft of the manuscript; X.Y. This week's topics include a nanoparticle vaccine for COVID, use of dexamethasone and surgical site infections, blood groups and disease . They noted that this area also includes a genetic variant associated with increased levels of interleukin-6, which plays a role in inflammation and may have implications for COVID-19 as well. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. This is why learning from Body Ecology, from doctors, and from other practitioners in our space is important. But you shouldn't be worried about any increase in side effects here, Dr. Martinello explains, as FDA regulators have seen a similar bivalent booster vaccine made by Pfizer and BioNTech for the "stealth" Omicron variant that spread rampantly last winter and those bivalent boosters were extensively studied before they were rolled out. Rare heart inflammation cases (around one in 6000) were reported in teenagers after their COVID-19 vaccination. She missed 2 doses of danicopan immediately after her second vaccination due to concerns that the drug may interfere with vaccine potency; therefore, danicopan was not at therapeutic levels at the time of her reaction. These cases have been mild and self-resolving. Swollen Lymph Nodes After COVID-19 Vaccines May Cause Mammogram Confusion. Annex V In both trials, the most commonly reported side effects within a week of injection were: According to current FDA publications, there's also a chance that swelling may occur in lymph nodes within the same arm as the injection site. Flu and COVID-19: How Do the Illnesses Compare? Patients were identified based on self-report of receiving the vaccine. Researchers looked at health data from more than 14,000 patients with COVID-19 and found a slightly increased infection prevalence among non-O types.